This SOP details basic safe work practices to follow when working with 3D printers. To date, little is known about occupational exposures and potential exposure-related health effects related to 3D printing technology. While fine particles (FPs) and ultrafine particles (UFPs) in particular, are not well characterized, they have been shown to penetrate and irritate the skin, lungs, nerves and brain tissues. Elevated FP and UFP levels may cause adverse health effects (e.g. eye, nose and throat irritation, cardio-pulmonary mortality, strokes and asthma). The above SOP lists activities in lab that may pose a risk as well as techniques for mitigation. These guidelines must be followed for all work with 3D printers. Contact EH&S for any additional questions.