Due to the hazardous nature of PCBs, it is required that testing of caulking and sealants for PCBs be included as part of the hazardous materials site assessment protocol process. PCBs have significant human health effects including being a suspect carcinogen. Regulatory agencies such as state department of environmental protection and U.S. EPA have regulatory requirements related to PCBs. Sampling and analysis testing should precede any alteration, renovation or demolition project involving campus buildings constructed between 1950 and 1977. If testing results reveal PCB levels in excess of 50 parts per million, specific actions under TSCA for disposal and an overall action plan must be developed and approved by EH&S before work commences.